Publications
The proprietary Porocell™ matrices are an improved form of poly-L-lactide (PLLA) foams which are highly optimized in porosity and structure and can be used for 3-dimensional cell culture applications and in vivo tissue engineering in animals. The use of PLLA foams for tissue engineering has been described in the literature.
A select list of references to PLLA matrix applications is given below:
Cell Transplant. 1997 Sep-Oct;6(5):463-8.
Highly porous polymer matrices as a three-dimensional culture system for hepatocytes.
Kaufmann PM, Heimrath S, Kim BS, Mooney DJ.
J Biosci. 2009 Dec;34(6):873-9.
Porous poly (L-lactic acid) scaffolds are optimal substrates for internal colonization by A6 mesoangioblasts and immunocytochemical analyses.
Carfí-Pavia F, Turturici G, Geraci F, Brucato V, La Carrubba V, Luparello C, Sconzo G.
J Biomed Mater Res A. 2010 Jan 20. [Epub ahead of print]
Determining the protein drug release characteristics and cell adhesion to a PLLA or PLGA biodegradable polymer membrane.
Burns SA, Hard R, Hicks WL Jr, Bright FV, Cohan D, Sigurdson L, Gardella JA Jr.
Cells Tissues Organs. 2001;169(1):34-41.
Optimization of hepatocyte spheroid formation for hepatic tissue engineering on three-dimensional biodegradable polymer within a flow bioreactor prior to implantation.
Török E, Pollok JM, Ma PX, Kaufmann PM, Dandri M, Petersen J, Burda MR, Kluth D, Perner F, Rogiers X.
